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What is a key difference between prokaryotic and eukaryotic chromosomes?


A) Prokaryotic chromosomes are coiled on histones; eukaryotic chromosomes are supercoiled
B) Prokaryotic chromosomes are linear; eukaryotic chromosomes are circular
C) Prokaryotic chromosomes are circular; eukaryotic chromosomes are linear

D) None of the above
E) All of the above

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Which of the following is true when proofreading by DNA polymerase?


A) it takes place long after a DNA strand has been replicated
B) it takes place as a DNA strand is being replicated
C) it is primarily possible because of mismatch repair enzymes

D) B) and C)
E) A) and C)

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What proteins are crucial for creating and maintaining DNA replication forks? Choose the best explanation.(Outcome #IIIb)


A) Helicase creates the replication fork; primase keeps the single strands from closing shut.
B) Helicase creates the replication fork; single-strand binding proteins keep the single strands from reuniting.
C) Ligase creates the replication fork; DNA polymerase II keeps the single strands from reuniting.

D) A) and C)
E) None of the above

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Experiments with bacteriophage by Chase and Hershey demonstrated that DNA replication is which of the following?


A) ultra-conservative
B) semi-conservative
C) moderate-to-liberal

D) A) and B)
E) A) and C)

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If a strand of DNA of sequence 5'-AATAGCGCGGTATTC-3' is replicated, which of the following accurately represents the newly synthesized DNA strand?


A) 3'-TTATCGCGCCATAAG-5'
B) 5'-TTATCGCGCCATAAG-3'
C) 3'-CCACTGTGTTACAAG-5'

D) None of the above
E) A) and C)

Correct Answer

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Which type of enzyme can repair DNA damage in eukaryotes?


A) DNA ligase
B) RNA primase
C) DNA polymerase

D) A) and B)
E) A) and C)

Correct Answer

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